Cytoscape Web
Click node...


4 associated genes
No signs/symptoms info
PROTEIN INTERACTIONS: 1
1 OMIM reference -
1 associated gene
5 signs/symptoms
Pediatric systemic lupus erythematosus
Pyogenic bacterial infections due to MyD88 deficiency

IRAK1 MYD88
PTPN22
SPP1
STAT4


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
IRAK1
(0.94)
MYD88



Citations in the biomedical literature:


Pediatric systemic lupus erythematosus
IRAK1 PTPN22 SPP1 STAT4
Pyogenic bacterial infections due to MyD88 deficiency
MYD88



Pediatric systemic lupus erythematosus
Pyogenic bacterial infections due to MyD88 deficiency

Synonym(s):
- SLE, pediatric onset

Synonym(s):
- MyD88 deficiency

Classification (Orphanet):
- Rare neurologic disease
- Rare renal disease
- Rare respiratory disease
- Rare systemic or rheumatologic disease
Classification (Orphanet):
- Rare genetic disease
- Rare immune disease

Classification (ICD10):
- Diseases of the musculoskeletal system and connective tissue -
Classification (ICD10):
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -

Epidemiological data:
(no data available)
Epidemiological data:
Class of prevalence: unknown
Average age onset: childhood
Average age of death: child / adolescent
Type of inheritance: autosomal recessive

External references:
No OMIM references
No MeSH references
External references:
1 OMIM reference -
No MeSH references

Pyogenic bacterial infections due to MyD88 deficiency

Very frequent
- Autosomal recessive inheritance
- Immunodeficiency / increased susceptibility to infections / recurrent infections

Frequent
- Chronic skin infection / ulcerations / ulcers / cancrum
- Nasal congestion / sinusitis / rhinitis / rhinorrhea

Occasional
- Fever / chilling


Pediatric systemic lupus erythematosus

(no data available)